Aconiazide References Navigation menu13410-86-1Interactive imageChEMBL15906744938702643357310.1016/0378-4347(95)00176-x854801610.1002/j.1875-9114.1994.tb02831.x7937278expanding ite

ProdrugsCarboxylic acidsHydrazidesPyridinesAntiinfective agent stubs


tuberculosisprodrug





















Aconiazide

Aconiazide.svg
Names

IUPAC name
2-[2-[(E)-(Pyridine-4-carbonylhydrazinylidene)methyl]phenoxy]acetic acid

Other names
Isonicophen; Phenoxalid

Identifiers

CAS Number


  • 13410-86-1


3D model (JSmol)


  • Interactive image


ChEMBL

  • ChEMBL1590674


ChemSpider

  • 4938702



PubChem CID


  • 6433573





Properties

Chemical formula


C15H13N3O4

Molar mass

7002299286000000000♠299.286 g·mol−1

Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).


Infobox references


Aconiazide is an anti-tuberculosis prodrug.[1][2]



References




  1. ^ Hansen Jr, EB; Dooley, KL; Thompson Jr, HC (1995). "High-performance liquid chromatographic analysis of the antituberculosis drugs aconiazide and isoniazid". Journal of Chromatography B. 670 (2): 259–66. doi:10.1016/0378-4347(95)00176-x. PMID 8548016..mw-parser-output cite.citationfont-style:inherit.mw-parser-output .citation qquotes:"""""""'""'".mw-parser-output .citation .cs1-lock-free abackground:url("//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png")no-repeat;background-position:right .1em center.mw-parser-output .citation .cs1-lock-limited a,.mw-parser-output .citation .cs1-lock-registration abackground:url("//upload.wikimedia.org/wikipedia/commons/thumb/d/d6/Lock-gray-alt-2.svg/9px-Lock-gray-alt-2.svg.png")no-repeat;background-position:right .1em center.mw-parser-output .citation .cs1-lock-subscription abackground:url("//upload.wikimedia.org/wikipedia/commons/thumb/a/aa/Lock-red-alt-2.svg/9px-Lock-red-alt-2.svg.png")no-repeat;background-position:right .1em center.mw-parser-output .cs1-subscription,.mw-parser-output .cs1-registrationcolor:#555.mw-parser-output .cs1-subscription span,.mw-parser-output .cs1-registration spanborder-bottom:1px dotted;cursor:help.mw-parser-output .cs1-ws-icon abackground:url("//upload.wikimedia.org/wikipedia/commons/thumb/4/4c/Wikisource-logo.svg/12px-Wikisource-logo.svg.png")no-repeat;background-position:right .1em center.mw-parser-output code.cs1-codecolor:inherit;background:inherit;border:inherit;padding:inherit.mw-parser-output .cs1-hidden-errordisplay:none;font-size:100%.mw-parser-output .cs1-visible-errorfont-size:100%.mw-parser-output .cs1-maintdisplay:none;color:#33aa33;margin-left:0.3em.mw-parser-output .cs1-subscription,.mw-parser-output .cs1-registration,.mw-parser-output .cs1-formatfont-size:95%.mw-parser-output .cs1-kern-left,.mw-parser-output .cs1-kern-wl-leftpadding-left:0.2em.mw-parser-output .cs1-kern-right,.mw-parser-output .cs1-kern-wl-rightpadding-right:0.2em


  2. ^ Peloquin, C. A.; James, G. T.; Craig, L. D.; Kim, M; McCarthy, E. A.; Iklé, D; Iseman, M. D. (1994). "Pharmacokinetic evaluation of aconiazide, a potentially less toxic isoniazid prodrug". Pharmacotherapy. 14 (4): 415–23. doi:10.1002/j.1875-9114.1994.tb02831.x. PMID 7937278.








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