Aloe emodin References See also Navigation menu481-72-1102079792C8IYT9CR7CC10294CHEBI:2607ChEMBL40275100.006.884Interactive image(verify)10.1002/mc.101701499174221031007e

AlizarinAloe emodinDamnacanthal1,3-Dihydroxyanthraquinone1,4-Dihydroxyanthraquinone1,8-DihydroxyanthraquinoneRheinCarminic acidSenna glycosides


Drugs not assigned an ATC codeDihydroxyanthraquinones


anthraquinoneemodinaloecarcinogenicaloe verasocotrine aloeBarbados aloe



































Aloe emodin
Aloe emodin.svg
Clinical data
SynonymsRhabarberone
Routes of
administration		Oral
ATC code
  • None
Identifiers
CAS Number

  • 481-72-1 ☒N

PubChem CID
  • 10207
ChemSpider

  • 9792 ☑Y
UNII
  • C8IYT9CR7C
KEGG

  • C10294 ☑Y
ChEBI

  • CHEBI:2607 ☒N
ChEMBL

  • ChEMBL40275 ☑Y
ECHA InfoCard
100.006.884 Edit this at Wikidata
Chemical and physical data
Formula
C15H10O5
Molar mass
7002270240000000000♠270.240 g·mol−1
3D model (JSmol)
  • Interactive image
Melting point223 to 224 °C (433 to 435 °F) Sublimes in CO2 stream

.mw-parser-output .noboldfont-weight:normal
 ☒N☑Y (what is this?)
  (verify)

Aloe emodin (1,8-dihydroxy-3-(hydroxymethyl)anthraquinone) is an anthraquinone and a variety of emodin present in aloe latex, an exudate from the aloe plant. It has a strong stimulant-laxative action.[1] Aloe emodin is not carcinogenic when applied to the skin, although it may increase the carcinogenicity of some kind of radiation.[2][3]


Aloe emodin is found in the gel, sap or leaves of aloe vera, the socotrine aloe, Barbados aloe, and Zanzibar aloes, the bark of Frangula (Rhamnus frangula) and cascara sagrada (Rhamnus purshiana), the leaves of Senna (Cassia angustifolia), and the rhizome of rhubarb (Rheum rhaponticum).[citation needed]
Aloe-emodin has not been found in Natal aloes.[citation needed]



References




  1. ^ The Merck Index, 12th Edition. 313


  2. ^ Badgwell, DB; Walker, CM; Baker, WT; Strickland, FM (2004). "Ethanol and aloe emodin alter the p53 mutational spectrum in ultraviolet radiation-induced murine skin tumors". Molecular Carcinogenesis. 39 (3): 127–38. doi:10.1002/mc.10170. PMID 14991742..mw-parser-output cite.citationfont-style:inherit.mw-parser-output .citation qquotes:"""""""'""'".mw-parser-output .citation .cs1-lock-free abackground:url("//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png")no-repeat;background-position:right .1em center.mw-parser-output .citation .cs1-lock-limited a,.mw-parser-output .citation .cs1-lock-registration abackground:url("//upload.wikimedia.org/wikipedia/commons/thumb/d/d6/Lock-gray-alt-2.svg/9px-Lock-gray-alt-2.svg.png")no-repeat;background-position:right .1em center.mw-parser-output .citation .cs1-lock-subscription abackground:url("//upload.wikimedia.org/wikipedia/commons/thumb/a/aa/Lock-red-alt-2.svg/9px-Lock-red-alt-2.svg.png")no-repeat;background-position:right .1em center.mw-parser-output .cs1-subscription,.mw-parser-output .cs1-registrationcolor:#555.mw-parser-output .cs1-subscription span,.mw-parser-output .cs1-registration spanborder-bottom:1px dotted;cursor:help.mw-parser-output .cs1-ws-icon abackground:url("//upload.wikimedia.org/wikipedia/commons/thumb/4/4c/Wikisource-logo.svg/12px-Wikisource-logo.svg.png")no-repeat;background-position:right .1em center.mw-parser-output code.cs1-codecolor:inherit;background:inherit;border:inherit;padding:inherit.mw-parser-output .cs1-hidden-errordisplay:none;font-size:100%.mw-parser-output .cs1-visible-errorfont-size:100%.mw-parser-output .cs1-maintdisplay:none;color:#33aa33;margin-left:0.3em.mw-parser-output .cs1-subscription,.mw-parser-output .cs1-registration,.mw-parser-output .cs1-formatfont-size:95%.mw-parser-output .cs1-kern-left,.mw-parser-output .cs1-kern-wl-leftpadding-left:0.2em.mw-parser-output .cs1-kern-right,.mw-parser-output .cs1-kern-wl-rightpadding-right:0.2em


  3. ^ National Toxicology, Program (2010). "Photocarcinogenesis study of aloe vera CAS NO. 481-72-1(Aloe-emodin) in SKH-1 mice (simulated solar light and topical application study)". National Toxicology Program Technical Report Series (553): 7–33, 35–97, 99–103 passim. PMID 21031007.




See also


  • Emodin






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